Conduct ingredient safety assessments leveraging next generation tools. Fill data gaps for new ingredients lacking existing literature for assessing safety. Apply next generation approaches appropriately and proficiently to inform on potential safe use of new ingredients.
Submit evaluation results in the proper format and within the time requested.
Perform systematic review for data and literature that is amenable to integration in an ingredient safety assessment. Identify appropriate new alternative methods (ie. high-throughput in vitro screening data, in silico models, etc.) to compliment in vivo data. Fill data gaps by integrating read-across and QSAR within an appropriate context. Describe and explain all approaches used as well as provide rationale on how to interpret/contextualize results to help the client gain confidence in utilizing next generation tools. Work within client deadlines and evolving needs as project progresses.
Conducted weight-of-evidence assessment by interpreting the next generation method data and outcomes to make decisions on ingredient safety. Provided report formatted per the client’s specifications (reports and publications). Effectively communicated with the client to provide updates on the methods used and to discuss the interpretation of the data. Worked closely with the client to ensure confidence in the results.